CAS 148553-50-8 Pregabalin

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1. What is the CAS 148553-50-8 Pregabalin ?

Pregabalin,CAS 148553-50-8, also named Lyrica,Pregabalin is an organic compound with a molecular formula of C8H17NO2, molecular weight of 159.23. Appearance is white powder.

2. CAS 148553-50-8 Pregabalin Description

Product Name: Pregabalin
Synonyms: 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;(3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;PREGABALIN;Pregablin;3-(Aminomethyl)-5-methyl-hexanoic acid;PREDNISOLONESODIUMPHOSPHATE;(R)-Pregabalin;(S)-Pregabalin
CAS: 148553-50-8
MF: C8H17NO2
MW: 159.23
EINECS: 604-639-1
Melting point 194-196°C
alpha D23 +10.52° (c = 1.06 in water)
Boiling point 274.0±23.0 °C(Predicted)
density 0.997±0.06 g/cm3(Predicted)
Fp 9℃
storage temp. 2-8°C
solubility deionized water: ≥10mg/mL
Uses S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.

3. What is CAS 148553-50-8 Pregabalin used for ?

Pregabalin is a new type of antiepileptic drug. Its molecular structure has a γ-aminobutyric acid structure, so it has anticonvulsant effect. It was successfully developed by Pfizer for the treatment of peripheral neuralgia or adjuvant treatment of partial seizures. . In December 2008, the U.S. Food and Drug Administration (FDA) approved pregabalin (trade name “Lerica”) for the treatment of both diabetic peripheral nerve pain (DPN) and post-herpetic neuralgia (PHN). The most common neuropathic pain. Neuropathic pain is one of the most difficult chronic pain syndromes to treat. It is characterized by dull, burning, and tingling pain. There are many causes of neuralgia. About 3% of the population in Europe suffers from neuralgia.

4. What is CAS 148553-50-8 Pregabalin Side Effect?

Studies have found that pregabalin can reduce the sensory and motor spinal reflexes of rat pinch toe stimulation, reduce the behavior related to diabetes, peripheral nerve injury or chemical treatment of neuropathic animal pain models, and inhibit or reduce the chemicalbook. Pain-related behaviors. Animal studies have found that pregabalin may have advantages in combination with opioids. Pregabalin for the clinical treatment of neuropathology.

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6.CAS 148553-50-8 Pregabalin Picture

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